Enclosed are the comments of eHealth Initiative (eHI) on the ONC Draft Trusted Exchange Framework (TEF) and the U.S. Core Data for Interoperability (USCDI). eHI is in a unique position to comment and offer insight on this issue. Our viewpoints are broad and consensus-based. We are the only independent non-profit, multi-stakeholder coalition dedicated to improving the quality, safety, and efficiency of healthcare through the use of technology and health information. Moreover, eHI’s work and its membership have built needed coalitions and moved the health IT field forward at critical junctures.