Choudhry et al. (2017) compared the effect of 3 low-cost reminder devices on medication adherence in a 4-arm, block-randomized clinical trial. Conclusion: Low-cost reminder devices did not improve adherence among nonadherent patients who were taking up to 3 medications to treat common chronic conditions. The devices may have been more effective if coupled with interventions to ensure consistent use or if targeted to individuals with an even higher risk of nonadherence.